South San Mateo Vacations from $409
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Your South San Mateo Vacation
With a vacation package to South San Mateo, you'll spend less time planning and more time experiencing this intriguing neighborhood. From its shopping to its dining, there's so much to discover here. Wondering where to go during your trip to South San Mateo? Nearby attractions like Hillsdale Shopping Center, Leo J. Ryan Park and Mariners Point Golf Center are excellent places to start. Whatever your travel plans or the size of your budget, booking your perfect South San Mateo vacation is a cinch with Expedia.
The Latest South San Mateo Vacation Packages
Hotel Riu Plaza Fisherman's Wharf
Reviewed on Sep 18, 2026
Where to stay in South San Mateo
Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
South San Mateo Hotel Deals
Holiday Inn Golden Gateway by IHG
"Good service"
Reviewed on Sep 18, 2026
Hotel Riu Plaza Fisherman's Wharf
"The continental breakfast was 1st class. Also like the fact that the hotel staff was very organized for the amount of people who ate breakfast."
Reviewed on Sep 18, 2026
Handlery Union Square Hotel
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Reviewed on Sep 18, 2026
Stay near popular South San Mateo attractions
San Mateo County Event Center
Hillsdale Shopping Center
Bay Meadows Park
Laurie Meadows Park
Casanova Park
Paddock Park
Sugarloaf Mountain
Fiesta Meadows Park
Things to do
Stanford University Personalized Self-Guided App Tour
Napa, Sonoma and Exclusive Battery Spencer Small Group Wine Tasting Tour
